Profanation – this legal term is used in the area of Canon Law, where it details the act of desecration, pollution. I.e. threating or using something that is sacred with irreverence. In other words – the act of profaning.
For example, within the sphere of Criminal Law in many legal systems, this term details a robbery of sacred goods in a church.
Also, the term could have the meaning of entering into the unworthy or improper usage of something.
Example: “Barbarians have done profanation of many temples and churches in the conquered lands.
Synonyms are blasphemy, defilement, desecration, impiety, and sacrilege.